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Updated: Jun 28, 2026
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Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
Published on: March 3, 2011
Hormonal replacement therapy and aging: Asian practical recommendations on testosterone supplementation
1Yonsei University College of Medicine, Korean Sexual and Men's Health Center, Han Central Bldg., 646-7 Yoksam-dong, Kangnam-ku 135-911 Seoul, Korea. youngkim2004@kornet.net
Asian Journal of Andrology
|December 30, 2003
Summary
Aging men experience hormonal changes, including declining testosterone. This summary provides practical guidelines for diagnosing and treating androgen deficiency in aging males to clarify common misconceptions.
Area of Science:
- Endocrinology
- Andrology
- Gerontology
Background:
- Aging is associated with significant alterations in gonadal and adrenal androgen production and growth hormone levels.
- The term 'partial endocrine deficiency in the aging male' (PEDAM) describes these hormonal changes.
- Key hormones affected include testosterone, dehydroepiandrosterone (DHEA), growth hormone, melatonin, thyroid hormones, and leptin.
Purpose of the Study:
- To address confusion and misunderstandings regarding the diagnosis and treatment of androgen deficiency in aging males.
- To provide practical criteria for the diagnosis and management of testosterone supplementation in aging men.
- To offer clinical considerations and Asian practical recommendations for testosterone supplementation.
Main Methods:
- Review of existing literature on hormonal changes associated with male aging.
- Analysis of clinical considerations for testosterone supplementation.
- Development of practical recommendations for diagnosis and treatment.
Main Results:
- Testosterone's effects on male bodily systems are well-researched, but its deficiency diagnosis and treatment remain areas of confusion.
- Practical criteria are needed to guide the appropriate use of testosterone therapy in aging men.
- Specific clinical considerations and regional recommendations are essential for effective management.
Conclusions:
- Clarifying the diagnosis and treatment of androgen deficiency is crucial for aging males.
- Evidence-based practical guidelines can help avoid misconceptions surrounding testosterone supplementation.
- Adopting standardized criteria and considering regional recommendations will improve patient care.
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