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Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

GRASP2: visualization, surface properties, and electrostatics of macromolecular structures and sequences.

Donald Petrey¹, Barry Honig

¹Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA.

Methods in Enzymology

|December 31, 2003

Summary

The new GRASP2 software enhances molecular visualization with advanced sequence and structure analysis tools. This update improves the integration of molecular data for researchers.

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Area of Science:

Computational Biology
Structural Bioinformatics
Molecular Modeling

Background:

The original GRASP software highlighted the significance of visualizing molecular physicochemical and structural properties.
Effective molecular surface visualization is crucial for understanding biological processes.

Purpose of the Study:

To introduce GRASP2, an advanced version of the GRASP software.
To detail the new capabilities and analysis tools offered by GRASP2.
To provide resources for accessing and learning about GRASP2.

Main Methods:

Description of new features in GRASP2, focusing on analysis tools.
Integration of sequence and structural information visualization.
Development of sequence and structure analysis and alignment tools.

Main Results:

GRASP2 incorporates enhanced capabilities for molecular surface analysis.
New tools facilitate sequence and structure analysis and alignment.
Graphical integration of sequence and structural data is now available.

Conclusions:

GRASP2 offers significant advancements over the original GRASP version.
The software continues to evolve with ongoing development and additions.
Resources are available for users to obtain and utilize GRASP2.