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Published on: February 28, 2012
Value of the implantable loop recorder for the management of patients with unexplained syncope
Lucas Boersma1, Lluís Mont, Alessandro Sionis
1Cardiology Department, St. Antonius Hospital, Heart Lung Center Utrecht, PO 2500, 3430 EM Nieuwegein, The Netherlands. l.boersma@antonius.net
Insights
The implantable loop recorder (ILR) effectively identifies cardiac arrhythmias causing unexplained syncope. This tool is more reliable than head-up tilt testing or electrophysiological studies for diagnosing syncope in patients with recurrent episodes.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Recurrent syncope is frequently unexplained despite comprehensive evaluations.
- Cardiac arrhythmias are a common but often elusive cause of syncope.
Purpose of the Study:
- To evaluate the diagnostic utility of the implantable loop recorder (ILR) in patients with unexplained recurrent syncope.
- To compare the effectiveness of ILR with traditional diagnostic methods like head-up tilt testing (HUTT) and electrophysiological study (EPS).
Main Methods:
- A prospective study involving 43 consecutive patients with unexplained syncope.
- Patients underwent extensive cardiological screening and subsequent monitoring with an ILR.
- Analysis of ILR data to correlate recorded events with syncope recurrence and identify underlying arrhythmias.
Main Results:
- The ILR successfully identified the cause of syncope in a significant portion of patients, including paroxysmal atrial fibrillation (PAF), ventricular tachycardia (VT), and various forms of bradycardia requiring pacemakers.
- In patients with true syncope recurrence, ILR detected arrhythmias in 8 out of 15 cases.
- Traditional screening methods showed abnormalities but lacked predictive value for syncope.
Conclusions:
- The implantable loop recorder (ILR) is a valuable and effective tool for establishing an arrhythmic cause of unexplained syncope.
- ILR offers superior diagnostic yield compared to HUTT and EPS in this patient population.
- Early implantation of ILR can expedite diagnosis and guide appropriate treatment for recurrent syncope.
Aim:
Recurrent syncope often remains unexplained despite extensive multidisciplinary screening. The implantable loop recorder (ILR) may be a tool to define the cardiac arrhythmias underlying syncope.
Methods And Results:
The study population consisted of 43 consecutive patients with unexplained syncope who underwent extensive cardiological screening and were followed with an ILR. During follow-up, 5 patients had only presyncope, 4 had palpitations, and 15 had a true recurrence of syncope. In all patients with palpitations, 3 with presyncope, and 7 with a recurrence of syncope, the ILR excluded arrhythmias. In the patients with a true recurrence, 1 had symptomatic paroxysmal atrial fibrillation (PAF) treated with drugs, 1 had polymorphic ventricular tachycardia (VT) and received an implantable cardioverter defibrillator (ICD), and 7 had asystole and received a pacemaker. Two patients with presyncope received a pacemaker for Mobitz II block and PAF with brady-tachycardia syndrome. One asymptomatic patient received a pacemaker for significant nocturnal asystole recorded by ILR. Abnormalities in the cardiac screening were observed both in patients with and without syncope, but none of these had a predictive value.
Conclusion:
The ILR is a valuable and effective tool to establish an arrhythmic cause for unexplained syncope. The results of head-up tilt testing (HUTT) and electrophysiological study (EPS) are neither sufficiently sensitive nor specific enough in this patient group.
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