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Anticoagulant peptides from Ancylostoma caninum are immunologically distinct and localize to separate structures

Juliusz Mieszczanek1, Lisa M Harrison, George P Vlasuk

  • 1Department of Pediatrics, Yale School of Medicine, Child Health Research Center, 464 Congress Avenue, New Haven, CT 06520-8081, USA.

Molecular and Biochemical Parasitology
|December 31, 2003
PubMed
Abstract

No abstract available in PubMed .

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Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
Cross-reactivity00:42

Cross-reactivity

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Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...

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