Related Experiment Video
Updated: Aug 29, 2026

A Neonatal Mouse Spinal Cord Compression Injury Model
Published on: March 27, 2016
Congenital formation of an intraspinal osseous vertebral ring causing spinal cord compression
Joshua Landa1, Albert E Telfeian, Denis S Drummond
1University of Pennsylvania, School of Medicine, Philadelphia, PA, USA. Jlanda@mail.med.upenn.edu
Study Design:
A unique case of the congenital formation of an intraspinal osseous vertebral ring causing spinal cord compression is reported.
Objectives:
To our knowledge, such an osseous ring has not yet been described. The authors detail the clinical presentation, imaging, and treatment of the intraspinal osseous ring.
Summary Of Background Data:
There are two traditional categories of congenital vertebral anomalies, that of failure of formation and of segmentation. The authors propose that this ring may not fit into either of these categories and may represent a new category of failure of migration.
Methods And Results:
Surgical decompression using a costotransversectomy approach was performed. Adequate decompression the spinal cord was achieved. Anterior and posterior fusions with instrumentation were used to stabilize the spinal cord.
Conclusions:
An intraspinal osseous vertebral ring is a unique anomaly that, to our knowledge, has not been reported to date. The authors discuss the pathology, imaging, and treatment of this unique condition.
Related Concept Videos
Spinal Cord Injury ll: Pathophysiology
Herniated Intervertebral Disc l: Introduction
Neurulation
Vertebral Column: Regions and Curvature
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form the...
Bone Formation by Endochondral Ossification
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
