CDK versus GSK-3 inhibition: a purple haze no longer?
1Cyclacel Limited, James Lindsay Place, Dundee, DD1 5JJ, Scotland.
Chemistry & Biology
|January 1, 2004
Abstract:
The ubiquitous ATP binding site offers a global target for protein kinase inhibitors. The corollary is that molecular selectivity with such agents may be difficult to achieve and ascertain. A relevant example is discussed in terms of design and biomedical rationale.
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