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Published on: September 20, 2018
Ocular rosacea in childhood
Sayeda Asad Nazir1, Scott Murphy, R Michael Siatkowski
1University of Oklahoma College of Medicine, Oklahoma City, Oklahoma, USA.
Insights
Pediatric ocular rosacea, characterized by eyelid inflammation and photophobia, often lacks skin symptoms and responds well to antibiotics. Long-term treatment may be needed for this condition in children.
Area of Science:
- Ophthalmology
- Dermatology
- Pediatrics
Background:
- Ocular rosacea is a common condition in adults, but its presentation and characteristics in children are less understood.
- This study focuses on the pediatric population, aiming to elucidate the specific clinical features and treatment outcomes of ocular rosacea in this age group.
Observation:
- The study reviewed six pediatric cases of ocular rosacea, with patients ranging from 3 to 12 years old.
- Common symptoms included chronic ocular irritation and photophobia. All patients exhibited eyelid telangiectases and meibomian gland disease, with half developing sterile corneal ulcers.
- Notably, only two patients showed cutaneous involvement, distinguishing pediatric cases from adult presentations.
Findings:
- Pediatric ocular rosacea often presents with bilateral eyelid inflammation and meibomian gland dysfunction, frequently without skin manifestations.
- Treatment with oral antibiotics, such as doxycycline or erythromycin, combined with topical agents, led to significant improvement in all patients.
- The condition can be misdiagnosed as infectious conjunctivitis due to similar inflammatory signs.
Implications:
- Early diagnosis and treatment of ocular rosacea in children are crucial to prevent complications like corneal ulcers.
- Understanding the distinct features in pediatric patients, particularly the rarity of cutaneous involvement, aids in accurate diagnosis.
- Long-term management strategies may be necessary to prevent recurrence and ensure sustained visual health in affected children.
Purpose:
To describe the clinical characteristics and treatment response of ocular rosacea in the pediatric population.
Design:
Retrospective case series.
Methods:
The clinic charts of consecutive pediatric cases of ocular rosacea were evaluated over a 34-month period. Minimal diagnostic inclusion criteria were the presence of posterior eyelid inflammation including meibomian gland inspissation and lid margin telangiectasis, in conjunction with conjunctival injection or episcleritis.
Results:
Six patients ranged from 3 to 12 years of age at presentation. All shared a long history of ocular irritation and photophobia. Five patients (83%) were female and had bilateral involvement. Eyelid telangiectases and meibomian gland disease were present in all cases. Three patients (50%) had sterile corneal ulcers. Only two patients (33%) had cutaneous involvement at the time of diagnosis. All patients experienced significant improvement with a combination of oral antibiotics (doxycycline or erythromycin), with or without topical antibiotics (erythromycin or bacitracin) or topical steroids (fluorometholone).
Conclusion:
Ocular rosacea in children may be misdiagnosed as viral or bacterial infections. Unlike in adults, associated cutaneous changes are uncommon. Most disease is bilateral, although involvement may be asymmetric. Response to conventional treatment is excellent, although long-term treatment may be necessary to prevent relapses.
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