Related Experiment Video
Updated: Aug 29, 2026
A Mouse Model for Corneal Neovascularization by Alkali Burn
Published on: June 30, 2023
Descemet membrane detachment with hemorrhage after alkali burn to the cornea
Dany M Najjar1, Christopher J Rapuano, Elisabeth J Cohen
1Cornea Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. danynajjar@hotmail.com
Purpose:
To report two cases of Descemet membrane detachment associated with hemorrhage after alkali burn to the cornea.
Design:
Observational case reports.
Methods:
We describe two patients with detachment of Descemet membrane associated with hemorrhage after alkali burns to the cornea.
Results:
Patient 1 received a splash of caustic soda to the face. Descemet membrane detachment with hemorrhage was present. An attempt at reattachment using intraocular gases failed. Patient 2 sustained a chemical burn secondary to an airbag injury. A thickened, detached Descemet membrane associated with a hyphema was evident.
Conclusions:
Detachments of Descemet membrane associated with alkali burns are often accompanied by irreversible endothelial cell damage.
