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[Morganella morganii and early-onset neonatal infection]

T Boussemart1, S Piet-Duroux, M Manouana

  • 1Service de pédiatrie B, CHRU de Pointe-à-Pitre, 97159 Pointe-à-Pitre, Guadeloupe. thierry.boussemart@wanadoo.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|January 1, 2004
PubMed
Abstract

Insights

This case report highlights a rare instance of Morganella morganii causing early-onset neonatal sepsis following maternal amoxicillin treatment. The study discusses the potential link between prior antibiotic use and the emergence of this opportunistic infection.

Area of Science:

  • Neonatal infections
  • Bacterial pathogenesis
  • Antimicrobial resistance

Background:

  • Morganella morganii is an opportunistic gram-negative bacterium.
  • It is known for resistance to ampicillin.
  • It is rarely implicated in early-onset neonatal sepsis.

Observation:

  • A pregnant patient received prophylactic amoxicillin after premature rupture of membranes.
  • She developed chorioamnionitis, and her infant was diagnosed with early-onset sepsis.
  • Maternal and infant blood cultures identified Morganella morganii.

Findings:

  • Both mother and infant were successfully treated with a third-generation cephalosporin and an aminoglycoside.
  • This case suggests a potential vertical transmission of M. morganii.

Implications:

  • The study discusses the influence of prior antibiotic therapy on the emergence of M. morganii vertical infections.
  • This finding may inform clinical practice regarding antibiotic use in pregnancy.
  • Further research is warranted to understand the role of M. morganii in neonatal sepsis.

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