Related Experiment Videos

Cranial computed tomography in purulent meningitis of childhood

Oguz Tuncer1, Hüseyin Caksen, Sükrü Arslan

  • 1Yüzüncü Yil University, Faculty of Medicine, Van, Turkey. oguztuncer76@lycos.com

Insights

Cranial computed tomography (CT) scans in children with purulent meningitis can identify complications. Abnormal CT findings at admission correlate with poorer outcomes, including sequelae and death.

Area of Science:

  • Pediatric Neurology
  • Radiology
  • Infectious Diseases

Background:

  • Purulent meningitis is a serious infection in children.
  • Cranial computed tomography (CT) is a key diagnostic tool.
  • Prognostic indicators for childhood meningitis require further investigation, especially in developing countries.

Purpose of the Study:

  • To assess the prognostic value of cranial CT findings in childhood purulent meningitis.
  • To determine the correlation between CT results and neurological signs.
  • To identify intracranial complications using CT in pediatric meningitis.

Main Methods:

  • Prospective examination of cranial CT scans in 48 children diagnosed with purulent meningitis.
  • Analysis of CT findings in relation to patient outcomes (survival without sequelae, survival with sequelae, death).
  • Correlation of CT results with neurological signs and follow-up CT scans.

Main Results:

  • Abnormal cranial CT findings at admission were significantly associated with poorer outcomes (p < .05).
  • CT scan results showed a significant correlation with neurological signs (p < .05).
  • Hydrocephalus and subdural effusion were the most frequent abnormal CT findings.

Conclusions:

  • Cranial CT is a safe and effective tool for detecting intracranial complications in childhood meningitis.
  • Abnormal CT findings are linked to a higher incidence of sequelae and mortality.
  • CT scan results correlate with neurological status, aiding in prognosis assessment.

Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...