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Panic attacks and psychoticism.

Renee D Goodwin1, David M Fergusson, L John Horwood

  • 1Department of Epidemiology, Columbia University, New York, NY 10032, USA. rdg66@columbia.edu

The American Journal of Psychiatry
|January 2, 2004
PubMed
Summary
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Adolescent panic attacks are linked to higher psychoticism rates in young adulthood. This association persists even after accounting for shared risk factors and other mental health conditions.

Area of Science:

  • Psychiatry
  • Developmental Psychology
  • Epidemiology

Background:

  • Panic attacks are a common mental health concern in adolescence.
  • Psychoticism is a personality trait associated with a predisposition to psychosis.
  • Understanding the relationship between these conditions is crucial for early intervention.

Purpose of the Study:

  • To investigate the longitudinal association between panic attacks in adolescence and psychoticism in young adulthood.
  • To determine if this association is independent of other risk factors and comorbidities.

Main Methods:

  • Utilized data from a 21-year longitudinal birth cohort study (N=1,265).
  • Employed negative binomial regression models to analyze the link between adolescent panic attacks (ages 15-21) and young adult psychoticism.

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  • Adjusted for confounding variables including prior psychoticism, anxiety, depression, and substance use disorders.

    • Main Results:

    • Panic attacks in the preceding 3 years were significantly associated with elevated psychoticism rates at ages 18 and 21.
    • The association remained significant after adjusting for potential confounding factors (rate ratio=1.51, 95% CI=1.14-2.02).
    • Common risk factors and psychiatric comorbidities explained a portion of the relationship, but an independent association was evident.

    Conclusions:

    • Adolescent panic attacks are independently associated with increased psychoticism levels in young adulthood.
    • Findings suggest a potential pathway from panic attacks to later psychotic experiences.
    • Further research is needed to replicate findings and elucidate the underlying mechanisms.