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Updated: Aug 29, 2026

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Aeromonas hydrophila and aspiration pneumonia: a diverse presentation
Chiranjoy Mukhopadhyay1, Anudita Bhargava, Archana Ayyagari
1Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India.
Abstract:
Although there are ever increasing reports of extraintestinal human infections caused by Aeromonads, in both immunocompromised and immunocompetent patients, respiratory tract infections remain uncommon. We describe a case of aspiration pneumonia in an immunocompetent patient with multiple sclerosis, caused by a community acquired, multidrug resistant strain of Aeromonas hydrophila sensitive only to meropenem. The case highlights the clinical significance of Aeromonas hydrophila as a respiratory pathogen, as well as the community origin of multidrug resistance and the utility of newer carbapenems in such cases.
Insights
Aeromonas hydrophila rarely causes respiratory infections, but this case shows it can lead to severe pneumonia in immunocompetent individuals. Multidrug resistance in the community and carbapenem effectiveness were also highlighted.
Area of Science:
- Infectious Diseases
- Microbiology
- Pulmonology
Background:
- Aeromonas species are increasingly recognized as causes of human infections, particularly extraintestinal infections.
- Respiratory tract infections due to Aeromonas species are considered uncommon in both immunocompromised and immunocompetent patients.
Observation:
- A case of aspiration pneumonia is described in an immunocompetent patient diagnosed with multiple sclerosis.
- The pneumonia was caused by a community-acquired Aeromonas hydrophila strain.
Findings:
- The identified Aeromonas hydrophila strain exhibited multidrug resistance.
- The pathogen was susceptible only to meropenem, a newer carbapenem.
Implications:
- This case underscores the potential of Aeromonas hydrophila to act as a significant respiratory pathogen.
- It highlights the emergence of multidrug resistance in community-acquired infections.
- The study emphasizes the clinical utility of carbapenems, such as meropenem, in treating such resistant infections.
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