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Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow
Published on: March 5, 2020
[In vitro and in vivo evaluation of the blood-biomaterial interaction]
E Cenni1, G Ciapetti, L Pratelli
1Centro di Ricerca Codivilla-Putti, Istituti Ortopedici Rizzoli, Bologna.
The Authors, after a short description of the phenomena following the interaction between blood and biomaterials, take into consideration the different methods used in studying the in vitro, in vivo and ex vivo hemocompatibility, as well as the problems involved by each method and its contribution to the knowledge of hemocompatibility. The Authors report their experience on the in vitro study of the effects induced by some biomaterials on platelets and coagulation factors.
The Authors, after a short description of the phenomena following the interaction between blood and biomaterials, take into consideration the different methods used in studying the in vitro, in vivo and ex vivo hemocompatibility, as well as the problems involved by each method and its contribution to the knowledge of hemocompatibility. The Authors report their experience on the in vitro study of the effects induced by some biomaterials on platelets and coagulation factors.

