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Effect of subthalamic deep brain stimulation on the function of the urinary bladder

Christoph Seif1, Jan Herzog, Christof van der Horst

  • 1Department of Urology, Christian-Albrechts-Universität Kiel, Kiel, Germany.

Annals of Neurology
|January 6, 2004
PubMed

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Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating urine...