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Takayasu's arteritis: vascular interventions and outcomes
Patrick Liang1, Millicent Tan-Ong, Gary S Hoffman
1Cleveland Clinic Foundation, Department of Rheumatic and Immunologic Diseases, Center for Vasculitis Care and Research, Cleveland, Ohio 44195, USA.
The Journal of Rheumatology
|January 6, 2004
Summary
Vascular interventions for Takayasu
Area of Science:
- Cardiovascular Medicine
- Vascular Surgery
- Rheumatology
Background:
- Takayasu's arteritis (TA) is a large-vessel vasculitis affecting the aorta and its branches.
- Vascular interventions are employed to restore blood flow in TA patients.
- Long-term outcomes of these interventions require careful evaluation.
Purpose of the Study:
- To analyze the outcomes of various vascular interventions in patients with Takayasu's arteritis.
- To assess vessel patency, complications, morbidity, and mortality following interventions.
Main Methods:
- Retrospective chart review of 20 patients with TA treated between 1979 and 2001.
- Vessel patency assessed via angiography or MRA.
- Interventions included bypass grafts, angioplasty (PTA), and stenting.
Main Results:
- 62 revascularization procedures were performed.
- Bypass grafts showed restenosis/occlusion in 11 of 31 cases.
- Endovascular procedures (PTA and stents) had high failure rates (3/7 PTA, 5/7 stents).
- No deaths occurred directly from revascularization procedures.
Conclusions:
- Vascular interventions offer short-term benefits for Takayasu's arteritis.
- Endovascular revascularization techniques demonstrate a high rate of failure in TA patients.
- Surgical approaches like bypass grafts also face challenges with long-term patency.