Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dentin extracellular matrix and dentinogenesis.

W T Butler1

  • 1University of Texas Health Science Center at Houston, Dental Branch.

Operative Dentistry
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Key proteolytic cleavage site and full-length form of DSPP.

Journal of dental research·2010
Same author

Different forms of DMP1 play distinct roles in mineralization.

Journal of dental research·2010
Same author

Importance of phosphorylation for osteopontin regulation of biomineralization.

Calcified tissue international·2005
Same author

Developmental analysis and computer modelling of bioengineered teeth.

Archives of oral biology·2005
Same author

Macrophages and mast cells control the neutrophil migration induced by dentin proteins.

Journal of dental research·2004
Same author

Dentin sialoprotein and phosphoprotein induce neutrophil recruitment: a mechanism dependent on IL-1beta, TNF-beta, and CXC chemokines.

Calcified tissue international·2004
Same journal

Academy of Operative Dentistry: Award of Excellence.

Operative dentistry·2026
Same journal

Effects of Charcoal-Based Mouthwashes on Color Change and Surface Roughness of a Stained Resin Composite.

Operative dentistry·2026
Same journal

Influence of Endodontic Access and Thermocycling on the Fracture Resistance of CAD/CAM Lithium Disilicate Anterior Crowns.

Operative dentistry·2026
Same journal

Color Match of Single-Shade and Group-Shade Resin Composites: A Visual and Instrumental Analysis.

Operative dentistry·2026
Same journal

Effect of Surface Treatment on the Characterization Layer of 3D-Printed and CAD/CAM Resin Composite Materials.

Operative dentistry·2026
Same journal

Cuspal Coverage Direct Resin Composite Restorations for Cracked Teeth: A Five-Year Clinical Study.

Operative dentistry·2026
See all related articles

Dentin formation involves odontoblast secretion of matrix proteins, crucial for transforming predentin into mineralized dentin. Key proteins like phosphophoryns and dentin sialoprotein guide this complex biomineralization process.

Area of Science:

  • Biochemistry
  • Cell Biology
  • Mineralization

Background:

  • Dentin formation is a complex biomineralization process.
  • Odontoblasts secrete matrix proteins before apatite crystal deposition.
  • Dentin collagen shares properties with bone, aiding protein binding and mineral scaffolding.

Purpose of the Study:

  • To investigate the role of dentin matrix proteins in dentinogenesis.
  • To understand the function of specific proteins like phosphophoryns and dentin sialoprotein.
  • To explore the relationship between bone and dentin proteins in odontoblast expression.

Main Methods:

  • Analysis of matrix protein secretion by odontoblasts.
  • Characterization of proteins at the mineralization front.

Related Experiment Videos

  • Comparison of dentin proteins with known bone proteins.

    • Main Results:

    • Matrix proteins secreted by odontoblasts are essential for predentin transformation.
    • Phosphophoryns and dentin sialoprotein are involved in circumpulpal dentin mineralization.
    • Dentin contains proteins also found in bone, expressed by odontoblasts.

    Conclusions:

    • Dentin matrix proteins play a critical role in dentinogenesis.
    • Further study of these proteins will elucidate the mechanisms of dentin formation.
    • Dentin sialoprotein may influence cell attachment, similar to bone proteins.