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Free radical scavenging activity of chitooligosaccharides by electron spin resonance spectrometry
Pyo-Jam Park1, Jae-Young Je, Se-Kwon Kim
1Department of Chemistry, Pukyong National University, Busan 608-737, Korea.
Abstract:
The radical scavenging effects of chitooligosaccharides (COSs) on hydroxyl radical, superoxide radical, alkyl radical, and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical were investigated using a spin-trapping electron spin resonance (ESR) method and compared with the ESR signal intensity. COSs exhibited strong scavenging activity on hydroxyl radical and superoxide radical and weak scavenging activity on alkyl radical and DPPH radical. The radical scavenging activity of COSs increased with increment of concentration, and it was also dependent on molecular weight. These results suggest that the scavenging activity of COSs is dependent on their molecular weights and tested radicals.
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