Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Risk factors for systemic emboli in infective endocarditis.

C Deprèle1, Ph Berthelot, F Lemetayer

  • 1Department of Infectious Diseases, University Hospital Saint Etienne, 42055 Saint Etienne Cedex 2, France.

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
|January 7, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence of scabies in Ouvea, New Caledonia: A population-based survey.

Annales de dermatologie et de venereologie·2026
Same author

Guidelines for tick-borne diseases (excluding Lyme borreliosis): diagnosis and management.

Infectious diseases now·2025
Same author

Molecular Ink-Based Synthesis of Bi(S<sub>z</sub>Se<sub>1-z</sub>)(I<sub>x</sub>Br<sub>1-x</sub>) Solid Solutions as Tuneable Materials for Sustainable Energy Applications.

Small methods·2025
Same author

[Health anxiety: Another epidemic to prepare for].

La Revue de medecine interne·2024
Same author

Efficacy of Mepolizumab for the Treatment of Eosinophilic Cystitis: A Report of 2 Cases.

Journal of investigational allergology & clinical immunology·2023
Same author

[Chronic fatigue: What investigations? And what for?]

La Revue de medecine interne·2023
Same journal

Impact of low-dose chest CT and multiplex PCR on antibiotic usage for community-acquired pneumonia: multicentre prospective controlled before-after study with cluster randomisation (CAP-NEXT study).

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same journal

Clinical Microbiology and Infection: how did we do in 2025?

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same journal

Automate the work, not the decision: aligning expectations for AI in clinical microbiology.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same journal

Doxycycline prophylaxis and gonococcal resistance: reassurance, residual signals, and the case for surveillance.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same journal

Oral metronidazole versus clindamycin to treat bacterial vaginosis in pregnancies at risk for preterm labor.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same journal

Efficacy and safety of a radiographic severity-stratified all-oral short treatment regimen for multidrug/rifampicin-resistant tuberculosis in China: An open-label, multi-center,randomized controlled, non-inferiority trial.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
See all related articles

Systemic emboli in infective endocarditis are significantly linked to vegetation size and mobility. Mobile vegetations exceeding 10 mm pose the highest risk for embolic episodes.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Echocardiography

Background:

  • Infective endocarditis (IE) is a serious infection of the heart valves.
  • Systemic emboli are a major complication of IE, leading to significant morbidity and mortality.
  • Identifying risk factors for emboli is crucial for patient management.

Purpose of the Study:

  • To analyze the risk factors associated with systemic emboli in patients diagnosed with infective endocarditis.
  • To determine the predictive value of vegetation characteristics on embolic events.

Main Methods:

  • Retrospective analysis of 80 patients with IE diagnosed via transoesophageal echocardiography (Duke criteria).
  • Comparison of 30 patients with embolic episodes against 50 control patients.

Related Experiment Videos

  • Univariate and multivariate analyses to identify risk factors for systemic emboli.

    • Main Results:

    • Vegetation size (mean 12.4 mm vs. 7.8 mm) and mobility were significant risk factors in univariate analysis.
    • Emboli risk was 57% for vegetations > 10 mm versus 22% for < 10 mm (p=0.003).
    • Mobile vegetations showed a higher risk (48%) compared to fixed ones (9%) (p=0.003). Multivariate analysis confirmed mobility as the sole significant risk factor.

    Conclusions:

    • Mobile vegetations, particularly those larger than 10 mm, are key predictors of systemic embolic events in infective endocarditis.
    • Vegetation mobility is a critical factor in assessing embolic risk in IE patients.
    • These findings aid in risk stratification and clinical decision-making for IE management.