Related Experiment Video
Updated: Aug 2, 2026
Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure
Published on: September 13, 2014
[Effects evaluation of middle mode artificial liver in treatment of severe hepatitis]
Nian-hai He1, Ying-jie Wang, Jun Liu
1Research Institute of Infectious Disease, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
Objective:
To evaluate the clinical efficacy and safety of middle mode artificial liver-plasma pheresis in treatment of severe hepatitis.
Methods:
Seventeen patients with severe hepatitis were treated with plasma pheresis. The results of liver function, renal function, blood routine, prothrombin time (PT), prothrombin time activity (PTa) before and after the treatment were analyzed. All patients were observed closely.
Results:
Symptoms of patients treated with plasma pheresis were improved, and the total effective rate reached 58.8 percent, but the survival rate was only 11.8 percent. Compared with those before the therapy, there were significant differences in aminotransferase, total bilirubin, direct bilirubin, PT, PTa and total protein level after treatment (P<0.05 or P<0.01). The side-effects were mild.
Conclusion:
Middle artificial liver is effective in the treatment of severe hepatitis.
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