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Updated: Aug 29, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

[Diagnostic images (169). A toddler not feeling well and having a rash. Eczema herpeticum]

P A Peters1, P A van Setten, F Brus

  • 1Ziekenhuis Rijnstate, afd. Kindergeneeskunde, Postbus 9555, 6800 TA Arnhem.

Nederlands Tijdschrift Voor Geneeskunde
|January 8, 2004
PubMed

Insights

Eczema herpeticum is a serious skin infection in infants. Early diagnosis and treatment are crucial for managing this condition in young children.

Area of Science:

  • Pediatrics
  • Dermatology
  • Infectious Diseases

Background:

  • Eczema, a common inflammatory skin condition, affects many infants.
  • Infants with eczema have a compromised skin barrier, increasing infection risk.
  • Herpetic infections can rapidly disseminate in infants with underlying skin conditions.

Observation:

  • A 1-year-old boy with a history of eczema presented with acute onset fever.
  • The patient developed a widespread vesicular rash.
  • Clinical presentation was suggestive of a severe cutaneous infection.

Findings:

  • The patient was diagnosed with eczema herpeticum, a viral infection.
  • Eczema herpeticum is a dermatological emergency.
  • Herpes simplex virus (HSV) is the common causative agent.

Implications:

  • Prompt recognition of eczema herpeticum is vital for preventing complications.
  • Antiviral therapy is the cornerstone of treatment.
  • Management requires a multidisciplinary approach involving pediatricians and dermatologists.

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