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[Chickenpox and pregnancy].

Y Vincent1, J P Bernard, M P Laroussinie

  • 1Service de Gynécologie-Obstétrique, Hôpital Boucicaut, Paris.

Revue Francaise De Gynecologie Et D'Obstetrique
|October 1, 1992
PubMed
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Chickenpox exposure in early pregnancy can lead to fetal infection, with signs appearing late in gestation. However, newborns may appear healthy initially, with later diagnosis confirmed by conditions like herpes zoster.

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Infectious Diseases in Pregnancy

Background:

  • Varicella-zoster virus (chickenpox) infection during pregnancy poses risks to both mother and fetus.
  • First-trimester maternal varicella infection can result in congenital varicella syndrome.
  • Monitoring fetal well-being is crucial following maternal exposure to infectious agents.

Observation:

  • A case of maternal chickenpox exposure during the first trimester of pregnancy is presented.
  • Antenatal ultrasonography detected fetal infection markers, including hepatomegaly, ascites, and pleural effusion, from 32 weeks of gestation.
  • The infant exhibited no abnormal clinical signs at birth.

Findings:

  • Postnatal diagnosis of fetal varicella infection was confirmed by the infant developing herpes zoster.

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  • Ultrasonographic findings of fetal infection did not correlate with the initial clinical presentation at birth.
  • The study highlights the challenges in predicting fetal prognosis in cases of maternal chickenpox.
  • Implications:

    • This case underscores the importance of vigilant fetal monitoring following maternal varicella exposure.
    • It emphasizes the potential for delayed clinical manifestation of congenital varicella infection.
    • Accurate fetal prognosis determination during pregnancy remains a significant clinical challenge.