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The role of glutathione in intestinal dysfunction
Heather Jefferies1, Joan Bot, Jane Coster
1Department of Surgery, University of Western Australia, Perth, Western Australia, Australia.
Abstract:
Glutathione plays an important cytoprotective role in the gut. Animal studies have demonstrated that the provisions of glutathione precursors are protective for different types of free-radical-mediated cellular injury. There is a need to clarify the potential role of glutathione supplementation in ischemia-reperfusion injury and inflammatory bowel disease. More speculative is whether treatment with glutathione precursors can modify the progress of colorectal cancer.