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Immunogenetical aspects of multiple sclerosis with special regard to the HLA-histocompatibility system
Bollettino Dell'Istituto Sieroterapico Milanese
|January 31, 1978
Abstract:
In the HLA complex it is evident that some antigens occur rather frequently, while others are rare. A statistically significant increase or decrease of any of these antigens in a given number of patients suffering from the same disease therefore suggests an association between such a disease and the HLA-system. In this study the Author compared the HLA antigen frequencies of 1.000 M.S. patients and 1.000 healthy controls, tissue typed during the same time period by the identical antiserum-set.