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SENV infection in HIV-positive patients: prevalence, subtype characterization, and impact on HIV disease progression
Eugenia Quiros-Roldan1, Carlo Torti, Luisa Imberti
1Department of Infectious and Tropical Diseases, Spedali Civili of Brescia, 25123, Italy. kaeniaquiros@hotmail.com
Abstract:
Among 165 HIV-infected patients, prevalence of SEN virus (SENV) infection was 51.5%, with subtype A predominance and unique SENV variant (67%), but also SENV superinfections with multiple variants were frequent. High prevalence, superinfection and broad SENV subtype diversification have been demonstrated, all linked to intravenous drug use (IVDU) as a risk factor for HIV acquisition. At multivariate analysis, SENV infection did not appear to have any negative impact on survival, while a possible protective effect needs further investigation.
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