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Updated: Aug 29, 2026

Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture
Published on: April 8, 2016
Non-Langerhan's cell histiocytoses of the skin
Naseem A Ansari1, Jihad T Al-Ratrout
1Department of Pathology, College of Medicine & Medical Sciences, Arabian Gulf University, Bahrain. ansarnas@hotmail.com
Abstract:
Histiocytic proliferations may be reactive or neoplastic. The neoplastic proliferations (histiocytoses) are subdivided into a few categories. One of these categories is the non-Langerhan's cell histiocytoses (NLCH). Cutaneous NLCH is a heterogeneous collection of conditions which can be sub grouped on the basis of the morphological appearance of the lesional histiocyte into xanthomatized, oncocytic, vacuolated, spindle-cell and polymorphous subtypes. The clinical characteristics and histological appearances of a variety of conditions within each subtype are discussed.
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