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Updated: Aug 22, 2026

A Model of Chronic Nutrient Infusion in the Rat
Published on: August 14, 2013
Nutritional support in critical care
Simon V Baudouin1, Timothy W Evans
1Department of Anaesthesia and Intensive Care Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK.
Abstract:
Despite the key role of nutrition in health and the almost universal use of supplemental feeding in the ICU, there is a lack of high-quality evidence to guide clinical practice. Enteral nutrition is superior to TPN in almost all circumstances and most patients in the ICU can be fed successfully by this route. There is little evidence to support the use of special feeds and the role of immunonutrients remains unproven. Nutritional support cannot completely prevent the adverse effects of catabolic illness and overfeeding should be avoided.
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