Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Primary cutaneous B-cell lymphomas: a practical approach.

Marie-France Demierre¹, Helmut Kerl, Rein Willemze

¹Department of Dermatology, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA. mariefrance.demierre@bmc.org

Hematology/Oncology Clinics of North America

|January 9, 2004

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mycosis Fungoides Palmaris et Plantaris.

JAMA dermatology·2025

Same author

European Organisation for Research and Treatment of Cancer, United States Cutaneous Lymphoma Consortium and International Society for Cutaneous Lymphomas consensus recommendations for management and treatment of cutaneous lymphoproliferative disorders.

The British journal of dermatology·2025

Same author

IgM Immunohistochemical Expression is a Potential Risk Factor for Extracutaneous Dissemination in Patients With Primary Cutaneous Follicle Center Lymphoma.

The American journal of surgical pathology·2025

Same author

Prognosis of increasing percentages of lesional body surface area in early stage mycosis fungoides.

Journal of the European Academy of Dermatology and Venereology : JEADV·2025

Same author

Added value of pathology consultations in cutaneous lymphomas: a 2-year review from the Dutch national referral and expertise centre.

The British journal of dermatology·2025

Same author

Phase II trial of atezolizumab (Anti-PD-L1) in the treatment of relapsed/refractory IIB/IVB mycosis fungoides/Sézary syndrome patients after previous systemic treatment. EORTC-1652-CLTG "PARCT".

European journal of cancer (Oxford, England : 1990)·2025

Primary cutaneous B-cell lymphomas (PCBCL) are skin lymphomas with a good prognosis. While recurrences are frequent, dissemination is rare, and chemotherapy is not the primary treatment.

Area of Science:

Dermatology
Oncology
Hematology

Background:

Primary cutaneous B-cell lymphomas (PCBCL) represent a diverse category of B-cell malignancies originating in the skin.
These lymphomas are characterized by the absence of extracutaneous disease at the time of initial diagnosis.
PCBCL generally exhibit an excellent prognosis, although recurrences are common, while systemic spread is infrequent.

Purpose of the Study:

To emphasize the importance of accurate diagnosis and classification of PCBCL.
To review available therapeutic strategies for PCBCL.
To provide guidance on appropriate first-line treatment for patients with PCBCL.

Main Methods:

Diagnosis relies on careful correlation of clinical presentation and pathological findings.

Related Experiment Videos

The European Organisation for Research and Treatment of Cancer (EORTC) classification facilitates standardized diagnosis and treatment planning.

Evaluation of various curative therapeutic options.

Main Results:

PCBCL are a heterogeneous group of B-cell lymphomas.
The prognosis for PCBCL is generally excellent.
Recurrences are common, but dissemination is rare.

Conclusions:

Accurate clinical and pathological correlation is crucial for diagnosing PCBCL before initiating treatment.
Several curative therapeutic options exist for PCBCL.
Chemotherapy is typically not recommended as the initial treatment for PCBCL.