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Related Experiment Videos

Plastic particles at the LASIK interface.

Anders Ivarsen1, Jan Thøgersen, Søren Rud Keiding

  • 1Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

Ophthalmology
|January 9, 2004
PubMed
Summary

During laser-assisted in situ keratomileusis (LASIK), plastic particles from the microkeratome are deposited at the interface. These particles persist for at least one year.

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Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Surgical Technology

Background:

  • Interface particles are frequently observed after LASIK surgery.
  • The origin and composition of these particles remain unclear.

Observation:

  • Thousands of brightly reflecting particles were observed in the LASIK interface of human patients and in rabbit corneas after microkeratome incision.
  • Particles were present immediately after incision, even without flap lifting, and persisted for up to one year.
  • Analysis revealed the particles were composed of polyetherimide, originating from the plastic segment of the microkeratome blade.

Findings:

  • Microkeratome oscillation generates numerous plastic particles (polyetherimide).
  • These particles are deposited at the corneal interface during LASIK.

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  • The particles are non-metallic, fluorescent, and persist unaltered for at least one year.

    • Implications:

    • Understanding the source of interface particles is crucial for ophthalmic surgery safety.
    • The persistence of these plastic particles may have long-term implications for corneal health.
    • Further research into microkeratome design and materials could mitigate particle generation.