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Determination of Fatty Acid Oxidation and Lipogenesis in Mouse Primary Hepatocytes
Published on: August 27, 2015
Protection from oxidative damage in mouse liver cells
A W Harman1, G M Adamson, S G Shaw
1Department of Pharmacology, University of Western Australia, Nedlands.
Toxicology Letters
|December 1, 1992
Abstract:
Paracetamol toxicity in mouse hepatocytes involved oxidative stress initiated by the formation of NAPQI. This oxidative component of paracetamol injury is associated with the latter stages of the poisoning process. Ebselen, a drug with GSH-peroxidase activity, was effective in ameliorating these oxidative events.
