Related Experiment Video
Updated: Aug 29, 2026
Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
Published on: July 18, 2016
[A retrospective study of advanced ovarian cancer in our ward]
Tsukasa Baba1, Yukiko Utsunomiya, Akiko Tamai
1Dept. of Obstetrics and Gynecology, Takamatsu Red Cross Hospital.
Objective:
To evaluate the efficacy of primary treatment for ovarian cancer from overall survival and progression-free survival.
Patients And Methods:
A total of 28 patients with epithelial ovarian cancer in stages III and IV who were primarily treated in our ward from 1993 were examined retrospectively. The Kaplan-Meier method and Harrington-Fleming test were carried out for the cumulative survival rate and analysis.
Results:
There were significant differences in the progression-free survival rate depending on whether or not optimal debulking was possible through primary treatment (p = 0.0128) and whether the histological diagnosis was serous adenocarcinoma (p = 0.038). In the serous adenocarcinoma group, the periods of both overall survival and progression-free survival were longer in treatment with taxanes and platinum than by other regimens, but in the endometrioid adenocarcinoma group, the period of progression-free survival was very short.
Conclusions:
Optimal debulking through primary treatment is critical in advanced ovarian cancer. Therapy with taxanes and platinum is efficacious for serous adenocarcinoma. The chemo-sensitivity of endometrioid adenocarcinoma is high, but the chemotherapeutic effect is only temporary.
