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Related Experiment Videos

Lack of correlation between aortic calcification and bone density.

P J Drinka1, S F Bauwens, A A DeSmet

  • 1Wisconsin Veterans Home, King 54946.

Wisconsin Medical Journal
|June 1, 1992
PubMed
Summary
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This study found no significant link between abdominal aortic calcification and bone mineral density in elderly men, even when accounting for age. Modern quantitative methods did not support previous suggestions of a connection between these aging-related conditions.

Area of Science:

  • Gerontology
  • Radiology
  • Bone Densitometry

Background:

  • Previous radiographic studies suggested a link between abdominal aortic calcification and osteoporosis.
  • This relationship has not been investigated using modern quantitative densitometry.

Purpose of the Study:

  • To quantitatively assess the relationship between aortic calcification and bone mineral density in elderly men using modern techniques.

Main Methods:

  • Aortic calcification was quantified from spinal radiographs in 112 elderly men.
  • Bone mineral density was measured at six sites using photon densitometry.
  • Statistical analysis controlled for the effect of age.

Main Results:

  • No significant correlation was found between aortic calcification and bone mineral density at any measured site.

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  • The absence of correlation persisted after adjusting for age.

    • Conclusions:

    • Quantitative densitometry did not support a positive relationship between abdominal aortic calcification and osteoporosis in elderly men.
    • Age-adjusted analysis indicates these degenerative processes may be independent in this population.