Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Angiogenesis and hematological malignancies].

Per Ole Iversen1

  • 1Institutt for ernaeringsforskning, Universitetet i Oslo, 0316 Oslo. poiversen@hotmail.com

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|January 10, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Micronutrient intake in adults with drug-resistant epilepsy treated with the modified Atkins diet needs monitoring.

Frontiers in nutrition·2026
Same author

Plasma Levels of Retinoids and Carotenoids in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation Given Extracorporeal Photopheresis to Prevent Graft-Versus-Host Disease-Analyses From a Randomized Trial.

EJHaem·2026
Same author

Toward ethical human microbiome research: improving health through radical interdisciplinary and intercultural co-laboration.

Microbiome·2026
Same author

DNA methylation of antiseizure medication metabolism genes and pharmacokinetic changes in adult epilepsy patients treated with the modified Atkins diet.

Genes & nutrition·2026
Same author

Extensive pregnancy-related off-treatment time in women with familial hypercholesterolaemia.

Atherosclerosis·2026
Same author

Research priorities for data science and artificial intelligence in global health: an international consensus exercise.

The Lancet. Global health·2026

Angiogenesis, the formation of new blood vessels, is linked to poor outcomes in blood cancers. Targeting this process may offer new therapeutic strategies for hematopoietic malignancies.

Area of Science:

  • Hematology
  • Oncology
  • Vascular Biology

Context:

  • Solid tumor growth and metastasis are known to involve angiogenesis.
  • Emerging evidence indicates angiogenesis also occurs in hematological malignancies.
  • This suggests angiogenesis as a potential therapeutic target in blood cancers.

Purpose:

  • To review the role of angiogenesis in hematological malignancies.
  • To explore the prognostic and therapeutic implications of angiogenesis in these cancers.

Summary:

  • Angiogenesis, characterized by increased blood vessel density in bone marrow, is associated with poor prognosis in hematopoietic malignancies.
  • While human treatment data are limited, animal studies suggest anti-angiogenesis therapies may inhibit leukemogenesis.
  • Malignant blood cell proliferation and spread appear linked to enhanced bone marrow angiogenesis.

Related Experiment Videos

Impact:

  • Findings highlight angiogenesis as a critical factor in hematopoietic malignancies.
  • Targeting angiogenic pathways could provide novel adjunct treatment strategies.
  • This research opens avenues for developing anti-angiogenesis therapies for blood cancers.