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Published on: March 8, 2012
Method for testing for human papillomavirus infection in patients with cervical intraepithelial disease
Hsing-Pei Lin1, Yang-Yang Huang, Hsueh-Yin Wu
1Department of Laboratory Medicine, Cathay General Hospital, Taipei, Taiwan, Republic of China.
Abstract:
To determine whether DNA detection of high-risk human papillomavirus could represent a reliable screening technique and a useful follow-up method, we investigated the performance of the Hybrid Capture II assay in detecting high-grade cervical lesions. The test positivity at 1.86 pg/ml had a high sensitivity (94.7%) and improved specificity. It was also a suitable follow-up method for detecting the recurrence of cervical intraepithelial disease in patients.