Related Experiment Video
Updated: Aug 4, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
Aspergillus infection of the airways: computed tomography and pathologic findings
Tomás Franquet1, Nestor L Müller, Anastasia Oikonomou
1Department of Radiology, Vancouver Hospital and Health Sciences Center, University of British Columbia, Vancouver, BC, Canada. 19429tfc@comb.es
Abstract:
Aspergillosis is a serious pathologic condition caused by Aspergillus organisms and is frequently seen in immunocompromised patients. In recent years, it has been shown that Aspergillus infection can result in a broad range of airway complications. In this article, we illustrate and review the characteristic computed tomography and pathologic findings of the different manifestations of Aspergillus infection involving the airways.
Insights
Aspergillosis, an Aspergillus infection, causes serious airway complications, especially in immunocompromised patients. This review details characteristic CT and pathologic findings of these airway manifestations.
Area of Science:
- Medical Mycology
- Pulmonology
- Radiology
Background:
- Aspergillosis is a significant opportunistic infection caused by Aspergillus species.
- It predominantly affects immunocompromised individuals, leading to severe health consequences.
- Airway complications are increasingly recognized manifestations of Aspergillus infection.
Purpose of the Study:
- To review and illustrate the diverse airway complications associated with Aspergillosis.
- To highlight the characteristic computed tomography (CT) findings.
- To correlate imaging findings with pathologic features of airway involvement.
Main Methods:
- Review of medical literature on Aspergillosis and airway complications.
- Analysis of characteristic computed tomography (CT) imaging.
- Correlation of imaging findings with pathological data.
Main Results:
- Aspergillosis can manifest in various ways within the airways.
- Characteristic CT findings are crucial for diagnosis.
- Pathologic examination confirms the extent and nature of airway damage.
Conclusions:
- Understanding the spectrum of airway complications in Aspergillosis is vital for timely diagnosis and management.
- Computed tomography (CT) plays a key role in identifying these complications.
- Integrated radiologic and pathologic assessment improves patient outcomes.
More Related Videos
15:01Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
Published on: September 18, 2021
10:06Efficient Method for Imaging Murine Lungs that Preserves Spatial Dynamics of Fungal Spores in the Airways
Published on: December 13, 2024
Related Concept Videos
Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Atypical Pneumonia