Related Experiment Video
Updated: Aug 29, 2026

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
Cardiovascular disease mortality
Anekwe E Onwuanyi1, Aubrey Clarke, Eric Vanderbush
1Morehouse School of Medicine, Division of Cardiology, Piedmont Hall, 720 Westview Drive SW, Atlanta, GA 30310, USA. aonwuany@msm.edu
Insights
Cardiovascular disease (CVD) mortality is high in urban Black populations. Hypertension-related deaths significantly contribute to excess CVD mortality in Central Harlem residents aged 25-64.
Area of Science:
- Public Health
- Epidemiology
- Cardiology
Background:
- Cardiovascular diseases (CVDs) remain a leading cause of death for urban Black populations in the U.S.
- Previous studies identified CVD as a major contributor to excess mortality in Central Harlem, but disease-specific data were lacking.
Purpose of the Study:
- To assess the distribution of specific cardiovascular diseases and their contribution to excess mortality in Central Harlem.
- To determine the primary drivers of cardiovascular mortality among Central Harlem residents.
Main Methods:
- Reviewed New York City (NYC) Department of Health vital statistics records for 1990.
- Identified cardiovascular deaths using the International Classification of Diseases (ICD), 9th Revision codes.
- Calculated total and disease-specific CVD mortality rates for NYC and Central Harlem using 1990 census data.
Main Results:
- Central Harlem residents aged 25-64 were at least twice as likely to die from cardiovascular causes compared to NYC residents.
- Hypertension-related deaths (ICD codes 401-404) were the leading cause of excess cardiovascular mortality for both men and women in Central Harlem.
Conclusions:
- Hypertension is the primary determinant of excess cardiovascular mortality in urban Black populations.
- Black residents of Central Harlem face an elevated risk of cardiovascular death, underscoring the need for targeted public health interventions.
Abstract:
Although mortality from cardiovascular diseases (CVDs) has been declining, it remains the leading cause of death among urban U.S. blacks. McCord and Freeman reported CVD as the major contributor to excess mortality in Central Harlem. However the disease-specific CVD mortality was not assessed. Thus, it was unclear what the distribution of specific CVDs was in Central Harlem and their contribution to excess mortality. We reviewed the vital statistics records of New York City (NYC) Department of Health for 1990 and identified all cases in which the cause of death was coded as cardiovascular (International Classification of Diseases-ICD, 9th Revision, codes 391, 393-398, 401-404, 410, 411, 414-417, 420-438 and 440-444). The total and disease-specific CVD mortality for NYC and Central Harlem were calculated using the appropriate 1990 census data as the denominator. Central Harlem residents aged between 25-64 years were at least twice as likely to die from cardiovascular causes, compared to NYC residents. Hypertension-related deaths, ICD codes 401 (essential hypertension), 402 (hypertensive heart disease), 403 (hypertensive renal disease), and 404 (hypertensive heart and renal disease), were the major cause of excess death for men and women in Central Harlem. These findings show the importance of hypertension as the main determinant of the excess cardiovascular mortality in urban blacks and suggest an increased risk of cardiovascular death in blacks residing in Central Harlem.
Related Concept Videos
Cardiovascular Drugs: Classification based on Therapeutic Indications
Coronary Artery Disease IV: Preventive Measures
Coronary Artery Disease I: Introduction
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Coronary Artery Disease III: Clinical Manifestations
Cardiomyopathy II: Dilated Cardiomyopathy