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Diffuse pulmonary infiltrates in hypogammaglobulinemia.
J Matz1, J M Routes, L C Borish
1Department of Medicine, National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado.
Annals of Allergy
|December 1, 1992
Summary
This case report details lymphangitic carcinomatosis from stomach adenocarcinoma mimicking interstitial lung disease in a patient with chronic venous hypertension (CVH). Early diagnosis and screening are crucial for CVH patients due to increased gastric cancer risk.
Area of Science:
- Gastroenterology
- Pulmonology
- Oncology
Background:
- Adenocarcinoma of the stomach presents with increased frequency and earlier onset in patients with chronic venous hypertension (CVH).
- Lymphangitic carcinomatosis is a rare presentation of metastatic cancer.
- Interstitial lung disease (ILD) can be caused by various conditions, including malignancy.
Observation:
- A case report of a patient with CVH presenting with symptoms suggestive of interstitial lung disease.
- The patient was diagnosed with lymphangitic carcinomatosis originating from adenocarcinoma of the stomach.
Findings:
- This is the first reported case of lymphangitic carcinomatosis from gastric adenocarcinoma presenting as ILD in a CVH patient.
- The findings highlight a critical diagnostic consideration in the evaluation of CVH patients with respiratory symptoms.
Implications:
- Clinicians should maintain a high index of suspicion for gastric adenocarcinoma in CVH patients with ILD-like presentations.
- Regular screening for gastric cancer, including stool occult blood tests and endoscopic evaluation for those with predisposing conditions (pernicious anemia, atrophic gastritis, achlorhydria), is recommended for CVH patients.