Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fatal necrotizing pneumonia caused by group A streptococcus.

A B Cengiz1, G Kanra, M Caĝlar

  • 1Department of Pediatric Infectious Disease, Hacettepe University Faculty of Medicine, Sihhiye, Ankara, Turkey. ateskara@hacettepe.edu.tr

Journal of Paediatrics and Child Health
|January 14, 2004
PubMed
Summary

Group A Streptococcus (GAS) can cause severe pneumonia in children, often progressing to sepsis and death. This case highlights the critical need to consider GAS in rapidly worsening childhood pneumonia cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>Aronia melanocarpa</i> extract modulates gut microbiota and induces dose-dependent metabolic shifts in broiler chickens.

British poultry science·2026
Same author

Response to the comment on "Enamel matrix derivative in the prevention and treatment of medication-related osteonecrosis of the jaws in rats".

International journal of oral and maxillofacial surgery·2026
Same author

Enamel matrix derivative in the prevention and treatment of medication-related osteonecrosis of the jaws in rats.

International journal of oral and maxillofacial surgery·2025
Same author

Role of Chronic Toxoplasmosis in Substance Abuse in Humans and its Effect on Dopamine Levels.

Nigerian journal of clinical practice·2025
Same author

Novel enabling strategies for oral peptide delivery.

International journal of pharmaceutics·2025
Same author

Scapholunate Ligament Partial Tears; Tear Localization, Extrinsic Ligament Injury Association and Conservative Treatment Responses Prior to Instability: Cross-Sectional Study.

Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca·2023

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Background:

  • Group A Streptococcus (GAS) is a significant pathogen causing various diseases, including invasive infections like pneumonia.
  • GAS pneumonia in children is often clinically overlooked, with limited recent literature focusing primarily on varicella-associated invasive GAS diseases.

Observation:

  • A previously healthy 7-year-old experienced community-acquired pneumonia that rapidly advanced to sepsis, respiratory failure, and fatality.
  • Autopsy revealed extensive lung tissue destruction, characterized by necrosis, edema, hemorrhage, and intense inflammation.

Findings:

  • Blood and pleural fluid cultures confirmed the presence of Streptococcus pyogenes, the causative agent of GAS.
  • Histopathological examination of lung tissue demonstrated severe inflammatory changes and tissue necrosis.

Related Experiment Videos

Implications:

  • This case underscores the importance of suspecting invasive GAS infection in children presenting with severe, rapidly deteriorating pneumonia.
  • Early recognition and appropriate antibiotic treatment for GAS are crucial to prevent severe outcomes and mortality in pediatric pneumonia.