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Cecilia Perret1, Katia Abarca, Jimena Ovalle

  • 1Pontificia Universidad Catolica de Chile School of Medicine, Virology Laboratory, Santiago, Chile. cperret@med.puc.cl

Emerging Infectious Diseases
|January 14, 2004
PubMed

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Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...