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Updated: Aug 4, 2026

The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis
Published on: February 19, 2013
[Colonic spirochetes: an infrequent cause of adult diarrhea]
I Amat Villegas1, E Borobio Aguilar, R Beloqui Perez
1Servicio de Anatomía Patológica, Hospital de Navarra, Pamplona, España.
Abstract:
Large intestine infection due to spirochetes was described in 1967 and is mainly related to two pathogens, Serpulina pilosicoli and Brachyspira aalborgi. Clinically, infection presents as diarrhea and/or rectorrhagia and is more frequent among homosexuals. Its prevalence is difficult to estimate but significant differences have been described according to the socioeconomic level of the area studied. We describe three cases of diarrhea due to spirochetes, which are of interest due to the lack of published cases in Spain. Based on these cases, we describe the main characteristics (morphological, therapeutic, etc.) of this infection.
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