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Budd-Chiari syndrome due to antithrombin III deficiency
Amit Jagtap1, Preeti Shanbag, Mamta Vaidya
1Department of Pediatrics, Lokmanya Tilak Medical College & General Hospital, Sion, Mumbai, India.
Budd-Chiari syndrome in a child was successfully treated using an inferior vena cava stent and anticoagulation. This case highlights congenital antithrombin III deficiency as a cause of Budd-Chiari syndrome.
Area of Science:
- Vascular Medicine
- Hematology
- Pediatric Gastroenterology
Background:
- Budd-Chiari syndrome is a rare condition causing liver vein obstruction and portal hypertension.
- Etiologies are diverse, including congenital and acquired thrombophilias.
Observation:
- A 2-year-old boy presented with symptoms suggestive of Budd-Chiari syndrome.
- Diagnostic workup revealed congenital antithrombin III deficiency as the underlying cause.
Findings:
- The patient underwent successful management with an expandable metal stent placed in the inferior vena cava.
- Long-term oral anticoagulation was initiated for the thrombophilia.
Implications:
- This case underscores the importance of investigating thrombophilic disorders in pediatric Budd-Chiari syndrome.
- Endovascular stenting offers a viable treatment option for inferior vena cava obstruction in this context.
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