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Acute acalculous cholecystitis and pancreatitis in a patient with concomitant leptospirosis and scrub typhus

Ning-Chi Wang1, Yuen-Hua Ni, Ming-Yieh Peng

  • 1Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.

Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi
|January 16, 2004
PubMed

Insights

Concomitant leptospirosis and scrub typhus coinfection is rare. This case highlights unusual complications like acute pancreatitis and cholecystitis in a patient with these infections.

Area of Science:

  • Infectious Diseases
  • Internal Medicine
  • Gastroenterology

Background:

  • Leptospirosis and scrub typhus are distinct infectious diseases with a wide range of clinical presentations.
  • Coinfection with both Leptospira and Orientia tsutsugamushi is uncommon.
  • Gastrointestinal complications such as acute pancreatitis and cholecystitis are rarely reported in adults with either infection.

Observation:

  • A 41-year-old male presented with symptoms indicative of coinfection.
  • The patient exhibited acute acalculous cholecystitis, pancreatitis, and acute renal failure.
  • Abdominal CT scan showed gallbladder edema but no intrahepatic or pancreatic lesions.

Findings:

  • The case confirms the rare occurrence of simultaneous leptospirosis and scrub typhus.
  • The coinfection presented with severe gastrointestinal and renal complications.
  • Successful treatment involved doxycycline, ceftriaxone, and supportive care.

Implications:

  • This case expands the known clinical spectrum of Leptospirosis and Scrub Typhus coinfection.
  • Highlights the importance of considering rare complications in dual infections.
  • Emphasizes prompt diagnosis and appropriate antibiotic therapy for improved patient outcomes.

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