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Miliaria crystallina in an intensive care setting.

N Haas1, F Martens, B M Henz

  • 1Departments of Dermatology, Medical Faculty (Charité), Humboldt-University Berlin, Schumannstrasse 20/21, 10117 Berlin, Germany. norb.haas@charite.de

Clinical and Experimental Dermatology
|January 16, 2004
PubMed
Summary

Miliaria crystallina, a skin condition causing small blisters, can occur with fever. In intensive care patients, enhanced alpha-adrenergic stimulation may contribute to its development.

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Area of Science:

  • Dermatology
  • Physiology

Background:

  • Miliaria crystallina presents as superficial, transient blisters due to sweat duct obstruction.
  • This condition is often associated with heat exposure or febrile states.
  • Sweat gland innervation involves both cholinergic and adrenergic pathways, which can be affected by medications.

Observation:

  • Two intensive care unit (ICU) patients experiencing fever developed miliaria crystallina.
  • These patients exhibited enhanced alpha-adrenergic stimulation.
  • The clinical presentation suggests a potential link between alpha-adrenergic activity and miliaria crystallina in febrile ICU patients.

Findings:

  • The study proposes that heightened alpha-adrenergic stimulation of sweat gland myoepithelia may precipitate miliaria crystallina.
  • This finding is based on observations in two specific febrile intensive care patients.

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Implications:

  • Understanding the role of adrenergic stimulation in miliaria crystallina can inform clinical management in intensive care settings.
  • Further research may elucidate the precise mechanisms linking adrenergic activity, fever, and sweat duct dysfunction.
  • This could lead to targeted interventions to prevent or treat miliaria crystallina in vulnerable patient populations.