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Updated: Aug 29, 2026

Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
Published on: September 20, 2021
[Experimental study of the effect of Astragalus membranaceus against herpes simplex virus type 1]
Objective:
To study the inhibitory effects of Astragalus membranaceus on herpes simplex virus type 1(HSV-1).
Methods:
In the 2BS cells infected with HSV-1, the antiviral effect of Astragalus membranaceus decoction was investigated by observing the inhibition of HSV-1-induced cytopathic effect in response to treatment with the decoction.
Results:
The half inhibition concentration (IC50) and minimal inhibition concentration (MIC) of Astragalus membranaceus were 0.98 and 1.95 g/ml respectively, with the therapeutic index (TI) of 128.
Conclusion:
Astragalus membranaceus has obvious HSV-1-inhibiting efficacy and low cytotoxicity.
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