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Updated: Aug 17, 2026

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Murine Prostate Micro-dissection and Surgical Castration
Published on: May 11, 2016
Epitestosterone--a potent competitive inhibitor of C21-steroid side chain cleavage in the testis
M Bicíková1, R Hampl, L Stárka
1Institute of Endocrinology, Praha, Czechoslovakia.
The Journal of Steroid Biochemistry and Molecular Biology
|December 1, 1992
Abstract:
Epitestosterone (17 alpha-hydroxy-4-androsten-3-one) inhibits both 17 alpha-hydroxylation and consequent side chain cleavage of the resulting 17 alpha-hydroxyprogesterone in the rat testicular microsomes. The inhibitory activity in terms of the Ki is 2 and 1.5 times as high, respectively, as that of cyproterone acetate.

