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Kawasaki disease in Oman--a clinical study

Sunil Kumar Bhatnagar1, George Paul, Raghavan Subramanian

  • 1Paediatric Infectious Diseases Unit, Division of Child Health, The Royal Hospital, Ministry of Health, Sultanate of Oman.

Journal of Tropical Pediatrics
|January 17, 2004
PubMed

Insights

Kawasaki disease in Omani children presents with oral lesions and elevated inflammatory markers. Intravenous immunoglobulin and aspirin therapy proved safe and effective for treatment.

Area of Science:

  • Pediatrics
  • Rheumatology
  • Epidemiology

Background:

  • Kawasaki disease is a critical pediatric illness affecting medium-sized arteries.
  • Understanding regional variations in Kawasaki disease presentation and outcomes is crucial for timely diagnosis and management.

Purpose of the Study:

  • To describe the clinical and laboratory features of Kawasaki disease in Omani children.
  • To evaluate the safety and efficacy of intravenous immunoglobulin and aspirin therapy in this population.

Main Methods:

  • Retrospective analysis of 39 pediatric patients diagnosed with Kawasaki disease between 1995 and 2002.
  • Review of case records for clinical manifestations, laboratory findings, and treatment outcomes.

Main Results:

  • The peak age of onset was 6-30 months, with a mean age of 29 months.
  • Oral lesions were present in all patients; elevated ESR and C-reactive protein were common.
  • Echocardiographic abnormalities occurred in 25% of cases, with coronary artery involvement in 12.5%.

Conclusions:

  • Kawasaki disease in Oman shares similarities with global presentations but highlights the importance of early diagnosis.
  • Intravenous immunoglobulin and aspirin therapy demonstrated safety and effectiveness in this cohort.

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