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Updated: Aug 29, 2026
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Disseminated squamous cell carcinoma of the skin
Orgun Deren1, Asuman Tuncel, Servet Gençağa
1Ankara Numune Training and Research Hospital, Mesa Camyolu Sitesi B-1, Blok D Giris No: 6, 06530 Cayyolu-Ankara, Turkey. orgunderen@yahoo.com
Background:
Squamous cell carcinoma (SCC) accounts for a large proportion of nonmelanoma skin cancers. It may appear mainly on the skin and the mucous membranes; however, it may also appear on any part of the body. The tumor originates from atypical keratinocytes. This tumor, which can be locally destructive, has a metastasis rate of 5% to 10%.
Objective:
To present a patient with disseminated primary SCC of the skin.
Methods:
In this report, we present a unique case of disseminated SCC that is thought to be primary. As far as we know, the patient neither had any syndrome or a disease predisposing to SCC nor was exposed to toxic substances or ionized radiation. The disease progressed in a very short period. To our knowledge, there has not so far been a case of disseminated primary SCC. The patient was inoperable when he presented to our clinic.
Results:
Chemotherapy was instituted in the Department of Medical Oncology; unfortunately, the patient died while on the therapy.
Conclusion:
An original case of disseminated SCC of the skin is presented.
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