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Updated: Aug 29, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
[In search of the best evidence]
Cristina Maria Galvão1, Namie Okino Sawada, Isabel Amélia Mendes
1Departamento de Enfermagem Geral e Especializada da EERP/USP.
Abstract:
Evidence-based practice is an approach involving the definition of a problem, the search for and critical evaluation of available evidence, the implementation of evidence in practice and the evaluation of the results obtained. In order to implement this approach in nursing, nurses must know how to obtain, interpret and integrate evidence stemming from research in the care rendered to patients and their relatives. Based on the literature, this article presents theoretical considerations concerning the hierarchy of evidence and where to search for the best evidence.
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