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High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions
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Social network analysis of gene expression data
Jung Hun Ohn1, Jihoon Kim, Ju Han Kim
1SNUBI: Seoul National University Biomedical Informatics, SNU School of Medicine, 110-799, Korea.
AMIA ... Annual Symposium Proceedings. AMIA Symposium
|January 20, 2004
Abstract:
To investigate the structure of genomic interaction network, social affiliation network analysis was performed for the yeast gene expression compendium dataset of hundreds of systematic perturbations. Network density and centrality indices of genes and groups of genes revealed the core-peripheral and the significant intermediary players that may be critical for the control of the biological system.
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01:42What is Gene Expression?
Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...
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