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Mouse models of human cancer web-based resources.

F Xu1, H Sahni, S Settnek

  • 1Center for Bioinformatics, National Cancer Institute, Rockville, Maryland, USA.

AMIA ... Annual Symposium Proceedings. AMIA Symposium
|January 20, 2004
PubMed
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The Mouse Models of Human Cancers Consortium (MMHCC) created accessible online resources for cancer research. These tools facilitate information and resource sharing among scientists studying human cancer mouse models.

Area of Science:

  • Oncology
  • Bioinformatics
  • Translational Cancer Research

Background:

  • The Mouse Models of Human Cancers Consortium (MMHCC) aims to generate and analyze mouse models that mimic human cancers.
  • Effective information and resource exchange is crucial for advancing cancer research.
  • Existing platforms may not adequately support the collaborative needs of MMHCC investigators.

Purpose of the Study:

  • To establish centralized, web-based resources for the MMHCC.
  • To improve data and resource sharing among cancer researchers.
  • To support the development and characterization of mouse models of human malignancies.

Main Methods:

  • Development of a dedicated website for the MMHCC.
  • Creation of specialized databases for cancer models.

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  • Implementation of a database for cancer images.
  • Leveraging the NCI Center for Bioinformatics (NCICB) infrastructure.

    • Main Results:

    • Launched a public website (http://emice.nci.nih.gov) for the MMHCC.
    • Established a searchable database for cancer models (http://cancermodels.nci.nih.gov).
    • Developed an image database (http://cancerimages.nci.nih.gov) for cancer research.
    • Ensured free availability of these resources to the cancer research community.

    Conclusions:

    • The developed web resources enhance collaboration and data accessibility for MMHCC.
    • These tools support the ongoing efforts in creating and utilizing mouse models for human cancer research.
    • The NCI Center for Bioinformatics provides a robust platform for scientific resource sharing.