Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A computer-generated stereotactic "Virtual Subdural Grid" to guide resective epilepsy surgery.

Kevin Morris1, Terence J O'Brien, Mark J Cook

  • 1Victorian Epilepsy Centre, the Centre for Clinical Neurosciences and Neurological Research, and the Departments of Medicine and Surgery, The University of Melbourne, St. Vincent's Hospital Melbourne, Victoria, Australia.

AJNR. American Journal of Neuroradiology
|January 20, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A neural mass modelling framework for evaluating EEG source localisation of seizure activity.

Journal of neural engineering·2026
Same author

Investigation of stress hormones across multiday seizure cycles.

Brain communications·2026
Same author

When seizure counts are not seizures: Measurement error and its implications for epilepsy management and driving policy.

Epilepsia·2026
Same author

The costs and benefits of an early access scheme for oncology medicines in Ireland.

BMC health services research·2026
Same author

Feasibility and signal quality of the Minder® implantable continuous EEG monitoring® system compared to 10-20 scalp electrodes over extended monitoring periods.

Epilepsia·2026
Same author

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

A new computer-aided "Virtual Grid" method accurately maps subdural electrode grids for epilepsy surgery. This improves localization of the epileptogenic zone and guides precise cortical resections, minimizing surgical errors.

Area of Science:

  • Neurosurgery
  • Medical Imaging
  • Computational Anatomy

Background:

  • Subdural electrode grids are crucial for localizing the epileptogenic zone in epilepsy surgery.
  • Precisely correlating electrode positions with brain anatomy has been challenging.
  • Current methods lack accuracy in determining the relationship between electrodes and brain structures.

Purpose of the Study:

  • To describe and validate a novel computer-aided method for displaying subdural electrode grid positions.
  • To coregister virtual electrode representations with 3D brain models for image-guided surgery.
  • To enhance the accuracy of pre-surgical planning in epilepsy.

Main Methods:

  • A "Virtual Grid" system was developed using postimplantation CT or MR imaging.

Related Experiment Videos

  • Seventeen patients underwent surgical procedures with visual verification of actual and virtual grids.
  • Quantitative accuracy was assessed in five patients using an infrared stereotactic probe.

    • Main Results:

    • Visual inspection confirmed satisfactory accuracy of the Virtual Grid in all 17 patients.
    • Quantitative analysis showed mean errors of 3.4 mm for CT-derived and 2.5 mm for MR-derived electrode positions.
    • MR-derived positions trended towards higher accuracy, while CT offered faster processing.

    Conclusions:

    • The Virtual Grid method provides highly accurate localization of subdural electrodes using CT and MR data.
    • This technology has the potential to reduce surgical errors and improve the precision of cortical resections.
    • The Virtual Grid system enhances pre-surgical planning for epilepsy surgery, optimizing patient outcomes.